SARS-CoV2 Existed in Lombardy ealier than the Wuhan Outbreak

Macrobius

Megaphoron
You've probably heard this claim. Here's a recent paper:


We conclude that a SARS-CoV-2 progenitor capable of producing a measles-like syndrome may have emerged in late June-late July 2019 and that viruses with mutations characterizing B.1 strain may have been spreading globally before the first Wuhan outbreak.

Molecular evidence for SARS-CoV-2 in samples collected from patients with morbilliform eruptions since late 2019 in Lombardy, northern Italy​


Abstract​

As a reference laboratory for measles and rubella surveillance in Lombardy, we evaluated the association between SARS-CoV-2 infection and measles-like syndromes, providing preliminary evidence for undetected early circulation of SARS-CoV-2. Overall, 435 samples from 156 cases were investigated. RNA from oropharyngeal swabs (N = 148) and urine (N = 141) was screened with four hemi-nested PCRs and molecular evidence for SARS-CoV-2 infection was found in 13 subjects. Two of the positive patients were from the pandemic period (2/12, 16.7%, March 2020–March 2021) and 11 were from the pre-pandemic period (11/44, 25%, August 2019–February 2020). Sera (N = 146) were tested for anti-SARS-CoV-2 IgG, IgM, and IgA antibodies. Five of the RNA-positive individuals also had detectable anti-SARS-CoV-2 antibodies. No strong evidence of infection was found in samples collected between August 2018 and July 2019 from 100 patients. The earliest sample with evidence of SARS-CoV-2 RNA was from September 12, 2019, and the positive patient was also positive for anti-SARS-CoV-2 antibodies (IgG and IgM). Mutations typical of B.1 strains previously reported to have emerged in January 2020 (C3037T, C14408T, and A23403G), were identified in samples collected as early as October 2019 in Lombardy. One of these mutations (C14408T) was also identified among sequences downloaded from public databases that were obtained by others from samples collected in Brazil in November 2019. We conclude that a SARS-CoV-2 progenitor capable of producing a measles-like syndrome may have emerged in late June-late July 2019 and that viruses with mutations characterizing B.1 strain may have been spreading globally before the first Wuhan outbreak. Our findings should be complemented by high-throughput sequencing to obtain additional sequence information. We highlight the importance of retrospective surveillance studies in understanding the early dynamics of COVID-19 spread and we encourage other groups to perform retrospective investigations to seek confirmatory proofs of early SARS-CoV-2 circulation.
 

Macrobius

Megaphoron
Since all three β mutations were present in samples collected on
October 17, 2019, we estimate that the progenitor of SARS-CoV-2 could
have already existed 11.6–16.2 weeks earlier than October 17, i.e., in
late June 2019 to late July 2019, using a simple extrapolation assuming
six mutations from the ancestral genome, constant substitution rate, and
the published range of mutation rate estimates (Kumar et al., 2021;
Pekar et al., 2021). Given that only short partial sequences are available
and that the level of sequence divergence is low, more sophisticated
molecular clock methods, including those which allow for variable clock
rates (Miura et al., 2020; Fisher et al., 2021) are not directly applicable,
and estimate precision is likely low.

So, the Wuhan variant was already circulating globally a year before (and thus prior immunity *did* exist in some populations).

A lot of the collected evidence is from infants who had a measles like rash and were taken in by their parents. Since young children seldom develop COVID symptoms, and since older people dying is not unusual, the world co-existed with COVID for half a year or longer before the panic of March 2020, even if you count the highly transmissible and deadly (to the elderly) strain.

Also, notice that some circulating COVID today developed from the *pre-cursor* to the alpha/beta strain made famous by Wuhan. In reality, these strains (ancestor of omicron?) were already circulating in the wild in 2018, however this is not proven in the paper. You can see it, however, in the 'bad flu season of 2018' -- esp. in the US midwest where human waste was sprayed (as aerosol) on corn fields, as fertilizer. This, in particular, is why the deer population of the midwest has the omicron strain endemic now.

Also notice the implication that, *if* any zoonotic explanation for the Wuhan strain (which may well not have originated in Wuhan, or if it did, was in the Chinese worker population in Milan in mid 2019, say) -- the worldwide spread of COVID producing coronaviruses must have happened *before* the alpha strain -- it is very unlikely that two separate wild branches of COVID sharing none of the alpha mutation and its descending clade, would both and simultaneously have 'made the hop to humans'. The innovation of 'alpha' is enhanced transmission, enhanced R0, and enchanced mortality.

In short, the 'two disease' hypothesis is correct, in that both versions were circulating worldwide, well before the Wuhan outbreak of October-December 2019, doubtless based on a mutation created in a laboratory, or a natural evolution of the precursor.
 
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Macrobius

Megaphoron
Amazing that a mere 2.5 years after the world learned of COVID (and likely about 4 years since the omicron variant was widely circulating)... we get a series of articles finally discussing 'what might have happened'....

Publisher Unz as usual leading the way here


 

Gawn Chippin

Arachnocronymic Metaphoron
Covid has just been pollished into a moar refined menace:


...'It is especially concerning that this new US-government ePPP research - like the previous US-government ePPP research on chimeric SARS-related coronaviruses at Wuhan Institute of Virology that may have caused the pandemic...

1666076863687.png
 

Macrobius

Megaphoron


Backstory:


WTF!
The weaponization of Omicron is a crime against humanity.

Arrest these people.

This is Gain of Function. Image
GOF that results in more pathogenicity. Image Image
So they took wild type (more virulent) spike and put it into Omicron (more transmissible) right as they rolled out vaccines that target Omicron attenuated spike.

Great plan if you want a permanent vax whack-a-mole gravy train.

Boston University researchers’ testing of lab-made version of Covid virus draws government scrutinyResearch at Boston University that involved testing a lab-made hybrid version of the SARS-CoV-2 virus is garnering heated headlines alleging the scientists involved could have unleashed a new pathogen…https://www.statnews.com/2022/10/17...ion-of-covid-virus-draws-government-scrutiny/
Epic Bad Take

I’m already seeing letters flying to senators and representatives over this.

Some pay checks depend on a narrative of innocence. They need to stop giving these folks platforms while censoring the dissenting views.
Unroll available on Thread Reader


When this does finally leak,
I have solved the racist nomenclature problem for everyone.

BUhan-1

#BUhan1 Image
This same behavior has poisoned the lab safety debate.


Opinion | If You’re Hunting for Heresy, You Aren’t a ScientistJoseph Ladapo is being condemned for something so-called public-health experts do all the time.https://www.wsj.com/articles/if-you...a-vaccine-thorp-fauci-antiscience-11665920874

Archive: https://archive.ph/B4jnd
 
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Macrobius

Megaphoron
This alone is quite the extraordinary claim. To make this assertion one is already making series assumptions built on another set of assumptions built on further assumptions... Where shall we begin?

Wherever you like. What is your assessment of the claim made and the evidence for it?
 

Macrobius

Megaphoron
You know you are in trouble when you have to testify about your grant before Congress and they defund you.

So... not spread by Winged Bandicoots I take it? 'Humans are zoonotic too!'



Summary site of the issue: https://originofcovid.org/
 
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I confess, I
personally produced it
in a plenilunio
bei mein superior essence
cause so disgusted
of the stolta moltidudo
only ubermensch will
survive
 
To enlighten the joke,
I dont see any evidence of the existence of the "Corona"
and as science goes, something has to be proven to be / not that I must prove something of not being

We can merely consider two points

1) the tests
tests were completely unreliable - not because of some percentage of false positive and false negatives: teste are utterly unreliable besidedes any percentage
then, without tests, all the narrative/dictatorship like red-zones and patient-zero and contagious people and contagious places is over
(note that the inventor of such tests who claimed that he intended it for laboratory researches, not for diagnosis ( he had unmarked himself for such a practice) was found dead in 2021; and that the president of an african nation John Magufuli had made a blind-test for a fruit and a parrot, which were had been found both positive - found dead in 2021 as well.)

as tests were utterly unreliable they had to rely on the diagnosis

2) diagnosis
diagnosis do rely on symptoms, more than on evidence (evidence is a cough, a fever / the diagnosis is influenza)
and the diagnosis magically had all twisted in favor of "covid-19" whatever the evidence
from all the previous diagnosis, from the influenza as far as people injured after car incidents with only a broken bone occuring
.
Other evidence could have been the data of total deaths and hospitalizations - these data dont show any evidence of a new lethal contagion going on (besideds no government and neither the WHO have ever defined it a pandemic, because the numbers never had fit within the definition).
In the end, there is no evidence that an epidemic had occurred at all.
 
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